科研成果
课题组在玉米抗病遗传与分子互作领域取得的研究成果
2026年
(5项)GWA Study Identifies Two Positive Regulators of Mycotoxin Fumonisin B1 Tolerance in Arabidopsis
Yaxin Guan, Houpeng Wu, Zhiqing Wang, Chuang Liu, Wangsheng Zhu·Genes·2026
代表性成果DOI: https://doi.org/10.3390/genes17030348Inactivating SnRK1β1A promotes broad-spectrum disease resistance in rice
Guixin Yuan, Xunli Lu, Xingbin Wang, Mengfei Li, Shiwei Wang, Zhaoxiang Huang, Zhigang Li, Fengrui Zhang, Xin Zhang, Jun Yang, Hailong Guo, Vijai Bhadauria, Wang-Sheng Zhu, Wensheng Zhao, Meng Yuan, Jian-Min Zhou, You-Liang Peng·Nature·2026
DOI: https://doi.org/10.1038/s41586-026-10273-5Decoding Arabidopsis growth-defense trade-offs through ADR1-associated transcriptional networks
Donghui Hu, Jinge Wang, Rachelle R.Q. Lee, Zezhao Su, Wangsheng Zhu, Sang-Tae Kim, Eunyoung Chae·Cell Reports·2026
DOI: https://doi.org/10.1016/j.celrep.2026.117030GWA Study Identifies Two Positive Regulators of Mycotoxin Fumonisin B1 Tolerance in Arabidopsis
Yaxin Guan, Houpeng Wu, Zhiqing Wang, Chuang Liu, Wangsheng Zhu·Genes·2026
DOI: https://doi.org/10.3390/genes17030348Allelic variation in maize Malate Dehydrogenase 7 shapes promoter methylation and banded leaf and sheath blight resistance.
Luyang Wei, Junbin Chen, Chuang Liu, DanDan Liu, Meida Du, Shengfeng He, Wenyu Cheng, Vijai Bhadauria, You‐Liang Peng, Wangsheng Zhu·Advanced Science·2026
代表性成果DOI: https://doi.org/10.1002/advs.2025113562025年
(8项)Glycosylation disruption is a new virulence strategy for a plant fungal pathogen
Chuang Liu, Wangsheng Zhu·Nature Plants·2025
DOI: https://doi.org/10.1038/s41477-025-02113-7An apoplastic fungal effector disrupts N-glycosylation of ZmLecRK1, inducing its degradation to suppress disease resistance in maize
Chuang Liu, Junbin Chen, Zhenju Li, Zhen Zhang, Yuyang Luan, Hui Liu, Hongtian Liu, Jianhua Huang, Wangsheng Zhu·Nature Plants·2025
代表性成果DOI: https://doi.org/10.1038/s41477-025-02112-8一种玉米纹枯病抗病基因 GRMZM2G068455 及其应用
发明人：朱旺升, 魏露阳, 刘闯, 陈俊斌·专利号：ZL 2025 1 0531216.9·2025
植物模式识别受体:从遗传变异到抗病育种
何胜凤, 陈俊斌, 李振菊, 朱旺升*·植物病理学报·2025
A major trade-off between growth and defense in Arabidopsis thaliana can vanish in field conditions
Derek S. Lundberg, Sonja Kersten, Ezgi Mehmetoğlu Boz, Pratchaya Pramoj Na Ayutthaya, Wangsheng Zhu, Karin Poersch, Wei Yuan, Sophia Swartz, David Müller, Ilja Bezrukov, , Detlef Weigel·PLOS Biology·2025
DOI: https://doi.org/10.1371/journal.pbio.3003237RPSR1, a major quantitative trait locus for Pythium stalk rot resistance in maize
Shengfeng He, Junbin Chen, Chuang Liu, Dandan Liu, Lei Wang, Canxing Duan, Wangsheng Zhu·The Crop Journal·2025
DOI: https://doi.org/10.1016/j.cj.2024.12.009一种人工改造的玉米广谱抗病基因 ZmLecRK1 及其应用
发明人：朱旺升, 刘闯, 李振菊, 陈俊斌·专利号：ZL 2025 1 0519347.5·2025
植物免疫应答中的钙通道:从分子机制到抗病育种
刘丹丹#, 陈俊斌#, 杜美达, 朱旺升*·生命科学·2025
2024年
(2项)Natural variations of maize ZmLecRK1 determine its interaction with ZmBAK1 and resistance patterns to multiple pathogens
Zhenju Li, Junbin Chen, Chuang Liu, Shengfeng He, Mingyu Wang, Lei Wang, Vijai Bhadauria, Shiwei Wang, Wenyu Cheng, Hui Liu, Xiaohong Yang, Mingliang Xu, You-Liang Peng, Wangsheng Zhu·Molecular Plant·2024
代表性成果DOI: https://doi.org/10.1016/j.molp.2024.09.006A de novo Gene Promotes Seed Germination Under Drought Stress in Arabidopsis
Guang-Teng Jin, Yong-Chao Xu, Xing-Hui Hou, Juan Jiang, Xin-Xin Li, Jia-Hui Xiao, Yu-Tao Bian, Yan-Bo Gong, Ming-Yu Wang, Zhi-Qin Zhang, Yong E Zhang, Wang-Sheng Zhu, Yong-Xiu Liu, Ya-Long Guo·Molecular Biology and Evolution·2024
DOI: https://doi.org/10.1093/molbev/msae2622023年
(3项)The plant immune receptor SNC1 monitors helper NLRs targeted by a bacterial effector
Ming-Yu Wang, Jun-Bin Chen, Rui Wu, Hai-Long Guo, Yan Chen, Zhen-Ju Li, Lu-Yang Wei, Chuang Liu, Sheng-Feng He, Mei-Da Du, Ya-long Guo, You-Liang Peng, Jonathan D.G. Jones, Detlef Weigel, Jian-Hua Huang, Wang-Sheng Zhu·Cell Host & Microbe·2023
代表性成果DOI: https://doi.org/10.1016/j.chom.2023.10.006A dual‐subcellular localized β‐glucosidase confers pathogen and insect resistance without a yield penalty in maize
Chuang Liu, Shengfeng He, Junbin Chen, Mingyu Wang, Zhenju Li, Luyang Wei, Yan Chen, Meida Du, Dandan Liu, Cai Li, Chunju An, Vijai Bhadauria, Jinsheng Lai, Wangsheng Zhu·Plant Biotechnology Journal·2023
代表性成果DOI: https://doi.org/10.1111/pbi.14242Small proteins modulate ion-channel-like ACD6 to regulate immunity in Arabidopsis thaliana
Junbin Chen, Lei Li, Jong Hum Kim, Benjamin Neuhäuser, Mingyu Wang, Michael Thelen, Richard Hilleary, Yuan Chi, Luyang Wei, Kavita Venkataramani, Moises Exposito-Alonso, Chang Liu, Jakob Keck, A. Cristina Barragan, Rebecca Schwab, Ulrich Lutz, Zhen-Ming Pei, Sheng-Yang He, Uwe Ludewig, Detlef Weigel, Wangsheng Zhu·Molecular Cell·2023
代表性成果DOI: 10.1016/j.molcel.2023.10.0302021年
(2项)An LRR‐only protein promotes NLP‐triggered cell death and disease susceptibility by facilitating oligomerization of NLP in Arabidopsis
Jun‐Bin Chen, Shu‐Wen Bao, Ya‐Li Fang, Lu‐Yang Wei, Wang‐Sheng Zhu, You‐Liang Peng, Jun Fan·New Phytologist·2021
DOI: https://doi.org/10.1111/nph.17680A membrane-bound ankyrin repeat protein confers race-specific leaf rust disease resistance in wheat
Markus C. Kolodziej, Jyoti Singla, Javier Sánchez-Martín, Helen Zbinden, Hana Šimková, Miroslava Karafiátová, Jaroslav Doležel, Julien Gronnier, Manuel Poretti, Gaétan Glauser, Wangsheng Zhu, Philipp Köster, Cyril Zipfel, Thomas Wicker, Simon G. Krattinger, Beat Keller·Nature Communications·2021
DOI: https://doi.org/10.1038/s41467-020-20777-x2019年
(2项)Plant lamin-like proteins mediate chromatin tethering at the nuclear periphery
Bo Hu, Nan Wang, Xiuli Bi, Ezgi Süheyla Karaaslan, Anna-Lena Weber, Wangsheng Zhu, Kenneth Wayne Berendzen, Chang Liu·Genome Biology·2019
DOI: https://doi.org/10.1186/s13059-019-1694-3Genetic interactions and molecular evolution of the duplicated genes ICARUS2 and ICARUS1 help Arabidopsis plants adapt to different ambient temperatures.
Méndez-Vigo B, Ausín I, Zhu W, Mollá-Morales A, Balasubramanian S, Alonso-Blanco C·The Plant Cell·2019
DOI: https://doi.org/10.1105/tpc.18.009382018年
(2项)An efficient CRISPR vector toolbox for obtaining large deletions in Arabidopsis thaliana.
Wu R, Lucke M, Jang Y, Zhu W, Symeonidi E, Wang C, Fitz J, Xi W, Schwab R, Weigel D*. ·Plant Methods·2018
DOI: https://doi.org/10.1186/s13007-018-0330-7Modulation of ACD6 dependent hyper-immunity by natural alleles of an Arabidopsis thaliana NLR resistance gene.
Zhu W#, Zaidem M#, Van de Weyer A, Gutaker R, Chae E, Kim S, Bemm F, Li L, Schwab R, Unger F, Beha M, Demar M and Weigel D*·PLoS Genetics·2018
DOI: https://doi.org/10.1371/journal.pgen.10076282017年
(2项)easyGWAS: A cloud based platform for comparing the results of genome-wide association studies.
Grimm DG*, Roqueiro D, Salomé PA, Kleeberger S, Greshake B, Zhu W, Liu C, Lippert C, Stegle O, Schölkopf B, Weigel D, Borgwardt KM*·The Plant Cell·2017
DOI: https://doi.org/10.1105/tpc.16.00551Altered chromatin compaction and histone methylation drive non-additive gene expression in an interspecific Arabidopsis hybrid.
Zhu W#, Hu B, Becker C, Doğan E, Berendzen K, Weigel D* and Liu C#*·Genome Biology·2017
DOI: https://link.springer.com/article/10.1186/s13059-017-1281-42015年
(2项)Natural variation identifies ICARUS1, a universal gene required for cell proliferation and growth at high temperatures in Arabidopsis thaliana.
Zhu W#, Ausin I#, Seleznev A, Méndez-Vigo B, Picó FX, Sureshkumar S, Sundaramoorthi V, Bulach D, Powell D, Seemann T, Alonso-Blanco C*, Balasubramanian S*·PLoS Genetics·2015
DOI: https://doi.org/10.1371/journal.pgen.1005085Genetic architecture of natural variation in thermal response of Arabidopsis thaliana.
Sanchez-Bermejo E,# Zhu W#, Tasset C, Eimer H, Sureshkumar S, Singh R, Sundaramoorthi V, Colling L, Balasubramanian S*·Plant Physiology·2015
DOI: https://doi.org/10.1104/pp.15.00942